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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d87a9fcd5d55d5631217d21b7c99a6f4f17706a45a404c2d17663c591952c4' 
  AND token = 'TaBHK5nxouU+3o51sykZYtLRj/ZRbqk8iExRrhrxjTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}