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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4d49e76a7bfb18be154fe7b29f88885390e691c277aee14aad211637d8c19d' 
  AND token = '2x0G+FO5qG9c5VXTpOqhSyvIBWtF3NFcuUAWSNGGu9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}