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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19108f8f530b69c025e3faa122c63458df7e0d02e3251b516809734c6b4d599e' 
  AND token = 'cu9MZpdE9pf7rJTTnyoinjc8vcLO43/yq3/9yis1XTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}