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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc72d980d1140d0b39e12c24c5815d1355c5579d7028b6c04e1847153bfbe587' 
  AND token = 'rKxrPnb/T9FUwVoSvQkj+90hZtvnU/jRrSIWWRv4u4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}