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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422e45f718e2b5f2d0f21fd828ed0d3b86744205af57b60504eee9a008aada6d' 
  AND token = 'qIiiFoPJrdmmU+BK/f6DX4j88G3++gz7GaOh0eyKqD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}