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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a8bc3c16ddce1edee443e455a45414b0c8d48eb7516c283060e61aa045c0d70' 
  AND token = 'xsJw8FFK/JLR4SekB/pMszO5I6pDyLkHau/mObLcNKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}