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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ab9c15c9d780ca6128b0a3adf81308733f4cd462ca4e087bb0e4814e43dc911' 
  AND token = 'jiDm2cCJf274W/K/NyZ505L4f7RqfI6uIHicU0uqQiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}