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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce411213d6fa1472a1198197868a5977bd8e4f679c81722fcf5489d4a96f71a' 
  AND token = 'vKMunj9YRvynAd3Myi3PGgm3z4Ou1nJcdeMdCb3mglU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}