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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac73489f9957399e85769dc52ac829b7d182b0fce909974225e0586d91913266' 
  AND token = 'Uu8GdoAgOMr58d2AiiXmx0lSUooIWt2DD70wPp5BoY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}