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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10b12fa57154e8947a5fa08f5665610b73592969fa5ffab2be7d45c78c6de72' 
  AND token = 'RILtvPBdBM2keuwWSdOJmiRHEYhf5cZ+IvmY3XTC7DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}