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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13fc6800b2598a01456bd75b62f21f06eaa1ec1cbe81d6ccdd418ce55355bd91' 
  AND token = 'qKFw9b+bkYMm4G8P2/aOxBi8K4YLUqdVMAoc4cuzxm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}