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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050c36fe8444890ab8943ea9915c4b44f1f5019665341289a791ac1f6fcb4068' 
  AND token = 'lyC8AQ8eml+2NJMr8I2NqZBE/4VobyE37OuOXvn/o18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}