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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c42dbe0a96acd0625f7758f4bb655d06ac42c1b3f5e06d1f3c149ad2373b0c' 
  AND token = 'wXAIBdluGLYazoH2oNfhmCPcN656KIQzcd3cRY/RBwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}