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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f33e6c8262268b33b3349b1dc5c29f2ff40d67c02802dc163ca1799198eb117' 
  AND token = 'OinzvJA+Kvq1F5ynRY3C6jm5gQYfzJNKtSfLpeA8M1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}