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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f2bb381348be6d2ba49df67a6ec0a871cb0195b74c45102b77cdb8a8879c90' 
  AND token = 'ZMaqEWdnn98TrNSGwe2DyuQ18DmDg5nObFWwgCvBh/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}