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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36683b7ceacccba4dc915a02208f2440e7366346293551dd5fd1b27dcd9a5e40' 
  AND token = '1DbK4XwaUXhMKs3oUSMk29HNQQyTWSZgSs3PTALY4FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}