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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9ce6330502f887a72335386c125a0d29a8ec007157ca1ac24503bc09806171' 
  AND token = 'JQGJEqR8V0Lo08l8DvDUkYY4KKZZdihF5kSA2r7e7MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}