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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0019cfcfd59b63b4e26dcf0668a3edb9fc2aa86dac7264465a067399a04f0d1b' 
  AND token = '4ObBhUDh/vHcLwMzZza2JiRBa9qDqHJ0uYsR/6vsP4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}