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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2acd13b9760e1d641b83c7f91fc5dd859870af5e07f57838142493bb5ed0c4' 
  AND token = 'ZT3cbYLVXpUIS0otss9caRB73JVCAmBTYwitaYkfKdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}