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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e050c5bcdb1aa47e804c657677e2c01e56af4912ef4432576e1dc113fd20bf' 
  AND token = '59g1IQ+0edDNYIxNlWzMEX6hyjUTlx1tW7dni8+lP5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}