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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455dfd642e8abf73407e2273b8f90447f69be05d3afacc9d0bad8bdbb09e8146' 
  AND token = 'EEK7BsSTM3yg/QWaEE7z185bjmeG9XJ8gW+1YwIoArA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}