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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051395f44073f893fb7a5b9f256f54a715286ee3186113c3766d0f5e29a1656c' 
  AND token = 'KMDme/NvG3QRuQknl8ssMa4dIfhAel3Bc7Smu2VXNQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}