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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303f14ff37fd747f3f856f177a17eff5d11ed5f2b851c087f9997c52356cae1f' 
  AND token = '1unYe7eUBDiaoWfvuRJnL5UJOd0M2d9rRx+ZeKnUT8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}