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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5c39f1bd257259e98159b40baa1d231f3e268c50b6583d9282d0c3317caa9a' 
  AND token = 'HMePpIfu/zVlNPvttD51ct8wR63Zz48tLCez5u7nnLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}