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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9426f8db6b535fd63bee1bf0a08f23abbf62ae000f29f9f77b5b0af448aa3949' 
  AND token = 'ZOjKnQkxtTnJIMKTcJIYFTlXt6CVAmX8onw/BA10iLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}