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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed132c9c1b21c84bd29fdbca3470dfcbe4d5819f65c445044f49f118b6f4f18b' 
  AND token = 'hGD29nk0NJ1O+npYrWsyddP9bTIgFOKlC1YS3axaOpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}