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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8da7f27f81228cb5c2ec09627e501199f600646522d6a1d82849cf39b5676b7' 
  AND token = 'XSIGhEgupb5KToHSCIUdf15G22LXA07sbBQapiNNUPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}