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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdef43fa0ebd30ea034a8ae23920fb55f03889e2f37b06316a27920402d2230b' 
  AND token = 'bKDkO2nG7kkpbT3OkyEiwlnvWp0v3/LhLG9j/bpVyg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}