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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ffffbce6e8eb607f0f46a5ce7d19ec087f67dc15cdb48f9e4a6cd3322aa235' 
  AND token = 'd5Xn5TO1oL04DOT/Kk3CExTQILtL48wWx530898YHiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}