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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447a4a5f5092bc06303ddd0f2fe0b2d54a3b90e6e4f3bddd615b7f8c80bf5551' 
  AND token = '+nMHJ4lEg+oLMA0GTj+I0Y7gwLaMlhFfvqSgC0rMjsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}