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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b03f35ef51020a5e3df21ce1b485001a72ff8dfc853f2631b5bf186ba56626' 
  AND token = 'vGtjC2/5i2SLaL3gyQH3zSmdAtBILYmXXzMpmXB8RhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}