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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67de77c4afd1c8fd189d455d404263cc68a6ff8a712add14b891066345399352' 
  AND token = '8We6GJFfdjC+b2VQCbTPQo1yo2HtzlTGNBbrAFmkUyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}