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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '602649e5f169a4fcc36e755b8d77f2f71d20d2ff14c8dce2a3fc69c3ef886e48' 
  AND token = 'jsNN2IYbo6xQakt7WrljhsUQpZmQNBxzMSrVcU6EM3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}