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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1dd567d3815544920ae9e64d14646c4bf906dbcbf5b5fa8101fece2bd6e0023' 
  AND token = 'l2hR467Bzu894WApyqIcQU0NMDnR27RUEskoLAB9NiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}