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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3563e2ca80054e7d6019a00f9d14656b6a5a3f1517ceb2b5ceaf415b851be45d' 
  AND token = 'CjYkuLeEzfLx6U6ebVxj0X6kVw6VduFIkOwWY4ZGA+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}