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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b26eacf1ede591a9c8358f32aefbb1172c03a964172151e3a62a48820c7bd60' 
  AND token = 'ICLjRq7Jb6FxGdUP3J4bMIHZXL7vmih8TNMC6NxcTC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}