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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e81ea0bd7fb73d94a75447235bc9a2c05efc27cbbe2552da8a8de66eba0b9f' 
  AND token = 'oO6QZp49SSookbSzHWRgSRydnw8Gs4UKKVcTjWYePIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}