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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c0741bc5e30963dea8144aec075a8d0aea67fcd57183caedc8da7a789e00a8' 
  AND token = 'kveg1Qmih5YWm8Jmfsr9ompgSh09VsJytgf4gAumjxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}