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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe775c5034a1ed015fe1b020a25b6a0cfefd26ca8a98ddc55c62bc2709e831ed' 
  AND token = 'A9DK4M03p0+kGOb8u0rwfzAN27DB3YhpkvKxO7H1KpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}