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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a0edf4f8472240160c763d3a4c393079656fed8fb282e06f1a7dc1021d4d86' 
  AND token = 'KLWV/R2FeU/5465UJ7RuPUiG2vY/FS6Xzs63EJ8/nn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}