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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4cb646f91129e74fc760d10d4be0cc9eb21d678a754a1304bedbc3ddc7d1e2' 
  AND token = 'c3SZqyysDwGjO2x6SdoilVE0MUHtAFCyBuK3t7OVUx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}