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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8755d48ee4720c465617db0e358cf48cf4d80812f775d02c6506b0dc2d34787e' 
  AND token = '/UcoUfwdsMfc33eKhS7SenVuf0+oiPHGyBJauoo/51Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}