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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82aa5b9c62e3dd90f59251e8ebfc38f8c944a6781cc5b987a23ab09064997774' 
  AND token = 'JmWaI0JwqNaarOclbmsZFpMINf5CKvnhA0Ornlsh8e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}