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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da9992926a0cece69b4a670bee4c44982241b1335503a3d46ea88c9a0bec04a6' 
  AND token = '849ZYt//gvgt6gzF3OxoTx9CVIrTDQDtSV102da02tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}