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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb8d1482790b243b1f6173d1a991aee888f449e46c1e77b9649885a53d26c01' 
  AND token = 'MeAQEuUaqqmWwhvL28RKBsYab3+nogoaMDlXMnC9uHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}