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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a186f5b08f11ffe312dd5bfd3647eb0a47a601935ff402917f76f35cbba3b565' 
  AND token = 'Lw1rjLM/S6ZZTCuS1fBlUHxvaDTu2ojxaCEQj/mEqHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}