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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78a2f25fbb2122f67ca46bab3c17bd428e8f39669a5cfb2d56bc129dca42ce2' 
  AND token = '1YXKKRMBZGPr4CbNEkxNmDqb+ZeJsucV0SiwbpMqcNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}