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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9045499e238aa304f3dfdc9e5a6dcd33b4cc937150010cd0b6ded6b9f7138762' 
  AND token = 'BPo0rzG1tspCSG5mGRPCE+avyK1lxhk0XjiK3c7HmEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}