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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72754e5b1861d5e484f7535e944a85fb0eb954514ba8a81a869c807cd55f58b5' 
  AND token = '8/sQ9LFYOVXdos/CpPpdX/p8ZokwyAk/U+RgTw2C3yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}