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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f761f5695a82a672b780661bdf068c8c4bf4fe8e361397f11415df3909645b4' 
  AND token = 'zjAu/YNjARleH+f3blK0X3MXkt1VHYh1ShD4FsBu10k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}